FITC标记的β淀粉样蛋白前体蛋白结合蛋白2抗体

产品介绍background:

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008].

 

Function:

May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

 

Subunit:

Binds APP. 

 

Subcellular Location:

Nucleus. Cytoplasm

 

Post-translational modifications:

Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.