脂肪组织分化相关蛋白抗体

产品介绍background:
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

Function:
May be involved in development and maintenance of adipose tissue.

Subcellular Location:
Membrane; Peripheral membrane protein.

Tissue Specificity:
Milk lipid globules.

Post-translational modifications:
Acylated; primarily with C14, C16 and C18 fatty acids.

Similarity:
Belongs to the perilipin family.