客服服务
  • 1品质承诺

    公司的核心价值是诚信为本,质量第一,生化商城承诺如产品质量有问题,我们会免费更换产品或退款。

  • 2技术服务

    由从事生命科学研究的高级技术人才提供技术支持,务求协助广大科研工作者准确达成目标,共同创造骄人成绩。

  • 3配送服务

    生化商城在总部上海拥有自己的配送队伍,同时和各大快递公司建立了深厚的合作关系,保证产品准时到达。

腺苷酸激酶-1抗体

产品详细信息

产品货号:hj-1160A

英文:Adenylate Kinase 1

英文缩写

【友情提示】:

产品介绍background:
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008].

Function:
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth.

Subunit:
Monomer.

Subcellular Location:
Cytoplasm.

DISEASE:
Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD) [MIM:612631].

Similarity:
Belongs to the adenylate kinase family